I am now getting into the prednisone arena where insomnia is happening. Prednisone is not a nice drug. It makes you swell up, gain weight, and have a terrible moon face. Don’t get me started on the irritability as well. However, it is also a friend in that it helps us to heal and get over a flare. It can save our lives when our body is fighting itself. So many good and bad things about it. The best thing is that it is better than not having it at all.