List of autoimmune diseases

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I was researching autoimmune disease and  found this list of many of them. It is eye opening to say the least. I was amazed how many there are. I actually have several on the list. So, in my attempt to educate others on autoimmune diseases, here is the list I found from the webpage “American Autoimmune Related Diseases Association”:

List of Autoimmune and Autoimmune-Related Diseases

 

  • Acute Disseminated Encephalomyelitis (ADEM)
  • Acute necrotizing hemorrhagic leukoencephalitis
  • Addison’s disease
  • Agammaglobulinemia
  • Allergic asthma
  • Allergic rhinitis
  • Alopecia areata
  • Amyloidosis
  • Ankylosing spondylitis
  • Anti-GBM/Anti-TBM nephritis
  • Antiphospholipid syndrome (APS)
  • Autoimmune aplastic anemia
  • Autoimmune dysautonomia
  • Autoimmune hepatitis
  • Autoimmune hyperlipidemia
  • Autoimmune immunodeficiency
  • Autoimmune inner ear disease (AIED)
  • Autoimmune myocarditis
  • Autoimmune pancreatitis
  • Autoimmune retinopathy
  • Autoimmune thrombocytopenic purpura (ATP)
  • Autoimmune thyroid disease
  • Axonal & neuronal neuropathies
  • Balo disease
  • Behcet’s disease
  • Bullous pemphigoid
  • Cardiomyopathy
  • Castleman disease
  • Celiac sprue
  • Chagas disease
  • Chronic fatigue syndrome
  • Chronic inflammatory demyelinating polyneuropathy (CIDP)
  • Chronic recurrent multifocal ostomyelitis (CRMO) 
  • Churg-Strauss syndrome
  • Cicatricial pemphigoid/benign mucosal pemphigoid
  • Crohn’s disease
  • Cogans syndrome
  • Cold agglutinin disease
  • Congenital heart block
  • Coxsackie myocarditis
  • CREST disease
  • Essential mixed cryoglobulinemia
  • Demyelinating neuropathies
  • Dermatitis herpetiformis 
  • Dermatomyositis
  • Devic’s disease (neuromyelitis optica)
  • Discoid lupus
  • Dressler’s syndrome
  • Endometriosis
  • Eosinophilic fasciitis
  • Erythema nodosum
  • Experimental allergic encephalomyelitis
  • Evans syndrome
  • Fibromyalgia**
  • Fibrosing alveolitis
  • Giant cell arteritis (temporal arteritis)
  • Glomerulonephritis
  • Goodpasture’s syndrome
  • Graves’ disease
  • Guillain-Barre syndrome
  • Hashimoto’s encephalitis
  • Hashimoto’s thyroiditis
  • Hemolytic anemia
  • Henoch-Schonlein purpura
  • Herpes gestationis
  • Hypogammaglobulinemia
  • Idiopathic thrombocytopenic purpura (ITP)
  • IgA nephropathy
  • IgG4-related sclerosing disease
  • Immunoregulatory lipoproteins
  • Inclusion body myositis
  • Insulin-dependent diabetes (type1)
  • Interstitial cystitis
  • Juvenile arthritis
  • Juvenile diabetes
  • Kawasaki syndrome
  • Lambert-Eaton syndrome
  • Leukocytoclastic vasculitis
  • Lichen planus
  • Lichen sclerosus
  • Ligneous conjunctivitis
  • Linear IgA disease (LAD)
  • Lupus (SLE)
  • Lyme disease, chronic 
  • Meniere’s disease
  • Microscopic polyangiitis
  • Mixed connective tissue disease (MCTD)
  • Mooren’s ulcer
  • Mucha-Habermann disease
  • Multiple sclerosis
  • Myasthenia gravis
  • Myositis
  • Narcolepsy
  • Neuromyelitis optica (Devic’s)
  • Neutropenia
  • Ocular cicatricial pemphigoid
  • Optic neuritis
  • Palindromic rheumatism
  • PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus)
  • Paraneoplastic cerebellar degeneration
  • Paroxysmal nocturnal hemoglobinuria (PNH)
  • Parry Romberg syndrome
  • Parsonnage-Turner syndrome
  • Pars planitis (peripheral uveitis)
  • Pemphigus
  • Peripheral neuropathy
  • Perivenous encephalomyelitis
  • Pernicious anemia
  • POEMS syndrome
  • Polyarteritis nodosa
  • Type I, II, & III autoimmune polyglandular syndromes
  • Polymyalgia rheumatica
  • Polymyositis
  • Postmyocardial infarction syndrome
  • Postpericardiotomy syndrome
  • Progesterone dermatitis
  • Primary biliary cirrhosis
  • Primary sclerosing cholangitis 
  • Psoriasis
  • Psoriatic arthritis
  • Idiopathic pulmonary fibrosis
  • Pyoderma gangrenosum
  • Pure red cell aplasia
  • Raynauds phenomenon
  • Reflex sympathetic dystrophy
  • Reiter’s syndrome
  • Relapsing polychondritis
  • Restless legs syndrome
  • Retroperitoneal Fibrosis
  • Rheumatic fever
  • Rheumatoid arthritis
  • Sarcoidosis
  • Schmidt syndrome
  • Scleritis
  • Scleroderma
  • Sjogren’s syndrome
  • Sperm & testicular autoimmunity
  • Stiff person syndrome
  • Subacute bacterial endocarditis (SBE)
  • Susac’s syndrome
  • Sympathetic ophthalmia
  • Takayasu’s arteritis
  • Temporal arteritis/Giant cell arteritis
  • Thrombocytopenic purpura (TTP)
  • Tolosa-Hunt syndrome
  • Transverse myelitis
  • Ulcerative colitis
  • Undifferentiated connective tissue disease (UCTD)
  • Uveitis
  • Vasculitis
  • Vesiculobullous dermatosis
  • Vitiligo
  • Wegener’s granulomatosis

**NOTE Fibromyalgia and Chronic Fatigue are listed, not because they are autoimmune, but because many persons who suffer from them have associated autoimmune disease(s)

Your Stories Shared Here

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Hey everyone!

I decided to make this post so you all could share your stories of your journey with these autoimmune diseases. I honestly think that by sharing, it helps us in the day to day, knowing there are others that are dealing with the same issues.  So, please share your story by commenting on this post. I think it will help our community bonding and each of us personally. Thanks! ~Jen

Nervous System Involvement in Lupus

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I am studying up on this segment of lupus and the nervous system involvement. I have found several interesting sources of information and thought it would be nice to share them with you.

The first one is is from the LFA’s website. Here is the information they have:

The Nervous System

Lupus is an autoimmune disease that can affect almost any part
of your body, including your joints, skin, kidneys, heart, lungs, or blood.
Lupus can also affect the nervous system and brain. There are several terms
doctors use to describe this: neuropsychiatric lupus (NP-SLE), neurocognitive
dysfunction, or central nervous system lupus (CNS lupus). Your nervous system
has three parts, any of which may be affected by lupus.

    • The central nervous system (CNS) consists of the brain and the
      spinal cord.
  • The peripheral nervous system (PNS) is a network of nerves that connects the
    brain and spinal cord to the rest of the body, and gives skin and muscles the
    signals needed for sensation and movement.
  • The autonomic nervous system (ANS) allows communication between spinal and
    peripheral nerves and the brain and internal organs, and controls functions like
    breathing, blood flow, and heart rate.

People with lupus can experience a number of complications when
their nervous system is affected. The symptoms may come on suddenly or may come
and go, but they will vary depending upon the location and extent of the tissue
injury. These symptoms also can be present in other diseases, so diagnosing
lupus-related nervous system disorders is often difficult.

Neurologists are the physicians who specialize in the nervous
system. They may rely on a number of diagnostic tools to determine whether lupus
is involved in your cognitive problems:

    • x-rays
  • brain scans (magnetic resonance imaging (MRI) and computed tomography (CT)
  • electroencephalograms (to capture the electrical pattern of brain activity)
  • spinal tap (to examine fluid in the spinal column)

Behavioral and cognitive tests may also be done to find out if
your memory or other mental abilities have been affected.

Depending on the symptoms, a variety of medications are
available to treat lupus-related nervous system disorders, including
non-steroidal anti-inflammatory drugs, antimalarials, and steroids. Your
response to treatment may be rapid or gradual over several months. For many
people with lupus, nervous system involvement is completely
reversible.

Central Nervous System (CNS)

When lupus affects your central nervous system, many symptoms
may occur, including:

    • headaches
  • confusion
  • fatigue
  • depression
  • seizures
  • strokes
  • vision problems
  • mood swings
  • difficulty concentrating

Drugs used to treat lupus can cause side effects that are
similar to the symptoms of CNS lupus. If you have symptoms of CNS lupus you
should consult a neurologist who can determine which symptoms are side effects
of medication and which are due to lupus. The drugs most known for causing
symptoms like those of CNS lupus are:

  • Non-steroidal anti-inflammatory drugs (NSAIDs) – may cause
    headache, dizziness, confusion, and in rare instances, meningitis-like
    symptoms
  • Antimalarials – in very high doses (not usually given for
    lupus) may cause manic behavior, seizures, psychosis
  • Corticosteroids – may cause agitation, confusion, mood swings,
    psychosis, depression
  • Anti-hypertensive medications – may cause depression or loss of
    sex drive

A serious form of lupus called CNS vasculitis may occur when
there is inflammation of the blood vessels of the brain. Characterized by high
fevers, seizures, psychosis, and meningitis-like stiffness of the neck, CNS
vasculitis is the most dangerous form of lupus involving the nervous system and
usually requires hospitalization and high doses of corticosteroids to suppress
the inflammation.

Peripheral Nervous System (PNS)

The nerves of your peripheral nervous system control your motor
responses and sensation, so symptoms of numbness or tingling, or inability to
move a part of your body, may be the result of lupus affecting these nerves.
Known as peripheral neuropathies, symptoms of PNS nerve damage are caused by
inflammation of the nerves or by compression of the nerves due to swelling in
the tissue around them. The types of symptoms you might experience
include:

    • vision problems
  • facial pain
  • ringing in the ears
  • dizziness
  • drooping of an eyelid
  • carpel tunnel syndrome

Autonomic Nervous System (ANS)

The autonomic nervous system regulates many of your body’s
functions that happen almost automatically: heart rate, blood pressure, feeling
hot or cold, bladder and bowel functions, release of adrenalin, breathing,
sweating, and muscle movement. Lupus can cause these nerve signals to be
overactive, which can lead to a wide range of symptoms:

    • numbness
  • burning
  • tingling
  • mental confusion
  • headaches
  • gastrointestinal problems such as nausea, vomiting, constipation, or
    diarrhea

Raynaud’s phenomenon

Raynaud’s phenomenon is a condition of ANS involvement caused by
inflammation of nerves or blood vessels. Blood vessels in your hands and feet go
into spasm and restrict blood flow, usually as a reaction to cold temperatures,
with the tips of the fingers or toes turning red, white, or blue. Raynaud’s can
also cause pain, numbness, or tingling in fingers and/or toes. People who have
Raynaud’s phenomenon are advised to avoid cold conditions when possible, and may
have to wear gloves or mittens when in air-conditioned surroundings.

Livedo reticularis and palmar erythema are two other skin
disorders that may affect you if you have autonomic nerve damage. Both of these
conditions can cause a bluish, lacelike mottling under your skin, especially on
your legs, giving your skin a “fishnet” look.

Cognitive Dysfunction

As many as half of all people with lupus describe feelings of
confusion, fatigue, memory loss, and difficulty expressing their thoughts. This
collection of symptoms is termed cognitive dysfunction, although many people
call it “lupus fog.”

Cognitive dysfunction most often affects people with mild to
moderately active lupus. The causes of these symptoms, and the reasons that the
symptoms tend to come and go, are not known. Living with cognitive dysfunction
can be very frustrating. However, you can learn to improve your concentration
and lessen confusion and memory loss with a variety of coping skills, including
puzzles, games, biofeedback, using a daily appointment calendar, and balancing
daily activities to reduce stress.

Lupus Headache

Compared with the general population, people with lupus may be
twice as likely to experience migraine-like lupus headaches, commonly known as
lupus headaches. The features of lupus headaches are similar to migraines and
may be seen more often in people who also have Raynaud’s phenomenon. However,
headaches can also be caused by vasculitis, a symptom of active lupus due to
inflammation of the blood vessels. If you are experiencing headaches that are
not improved by an over-the-counter headache medication, be sure to tell your
doctor
s.

Restless Leg Syndrome

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I know several people who have this and so it seemed only natural to include an overview here. The name can be deceiving because it is not only associated with the legs. Please read so you can understand and learn more. It was an eye opening article for me. This information is from www.rls.org website. While this article is short, you can check into it more at the website and many others.

Restless Leg Syndrome

Restless legs syndrome (RLS) is a neurological condition that is characterized by the irresistible urge to move the legs. While the name may sound funny, it is a very real disorder. In order for you to be officially diagnosed with RLS, you must meet the criteria described in the four bullets below:

  • You have a strong urge to move your legs which you may not be able to resist. The need to move is often accompanied by uncomfortable sensations. Some words used to describe these sensations include: creeping, itching, pulling, creepy-crawly, tugging, or gnawing.
  • Your RLS symptoms start or become worse when you are resting. The longer you are resting, the greater the chance the symptoms will occur and the more severe they are likely to be.
  • Your RLS symptoms get better when you move your legs. The relief can be complete or only partial but generally starts very soon after starting an activity. Relief persists as long as the motor activity continues.
  • Your RLS symptoms are worse in the evening especially when you are lying down. Activities that bother you at night do not bother you during the day.

RLS can also cause difficulty in falling or staying asleep which can be one of the chief complaints of the syndrome. A substantial number of people who have RLS also have periodic limb movements of sleep (PLMS). These are jerks that occur every 20 to 30 seconds on and off throughout the night. This can cause partial awakenings that disrupt sleep. Sleep deprivation can seriously impact your work, relationships, and health.

Walking in a Winter Wonderland

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Ok, so the title is a bit misleading. If you see me walking in the snow, odds are it is an emergency of some kind or not by choice. Winter is brutal this year for me. Most of the time, when the cold hits I feel it at least a little. Some days more than others. This winter is different in that every time I go out, I pay for at least a day or so. How? In pain, that awful joint pain that throbs and makes you wish you could just cut off the offending member. Ok, so that is a bit on the dramatic side, I admit, however it does hurt like the dickens and makes you a bit on the crazy side. One of the saying I use at times like this is, “I am a pain, when I am in pain”. Don’t say I did not warn you!

The reason for this title is that here where I live, we are expecting a major snowstorm beginning tonight and going through Monday. Blowing and drifting snow will make it hard to travel as well as the snowfall amounts. So basically, I am housebound. Oh, I have all the necessities of life here, don’t get me wrong. I just mean that I cannot go out into the snow.

You see, I have osteoporosis in my spine from the steroids usage for the lupus. Yes, pick your poison, do you want to live, albeit with fragile bones, or just wing it and hope for the best? Well, I went with the steroids and they really do help. They also really have serious side effects, like osteoporosis among others. That means when it gets slippery outside, I stay inside. I like my hips and spine just the way they are thank you. One slip and fall and  I could be laid up for a long time!

So, when you are out and about in the winter wonderland, remember to enjoy it. There are those of us who would love to be out there and having snowball fights, making snow angels and such but we know our own fragilities and watch from the windows. We do not want pity. We just want understanding and empathy. It is not easy being different and watching others have fun. The alternative though, is the possible fracturing of bones and more pain. We want to survive to see another snowfall, watch another grandchild grow, and feel alive. In the future, please be more respectful of us. We do not want to be different, we just are.

Chemotherapy and Lupus

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Many of you who see this will think, what do these two have in common? The truth is, quite a lot. I personally have been on chemotherapy several times due to my lupus. Many of my lupie friends have as well. It is not well known to those outside of the lupus world though.

You see, lupus is an autoimmune disease, which means, that our bodies create antibodies against our own body and its cells. In effect, our body attacks itself. Antibodies are great when you are sick and need to fight an infection. When they go into hyper mode, you are now into the realm of autoimmune diseases.

Where does the chemotherapy come in, you ask? In an effort to slow down the autoimmune disease from being in hyper mode, we are given chemotherapy agents to shut it down, or at least attempt to take it down to a more normal level. Sometimes it works, sometimes it goes too far. It is a fine line on therapeutic effect and overkill.

I actually was on chemotherapy when I was “let go” from my last job. I had been told that my job would still be there while I was out on paid sick leave. The truth is, they fired me by email. They gathered my things up and federal expressed them to me too. How lovely. Ok, sorry, I am digressing into the land of the past and I need to let it go.

This information is from the Lupus Foundation of America website about chemotherapy:

“chemotherapy, is generally reserved for those individuals who have the most severe flares of lupus; or to enable the steroid dose to be reduced. A severe flare is one that affects an organ to the degree that the function is impaired. When this happens something has to be done to preserve the function of the organ and that’s when immunosuppressive or chemotherapy medications are prescribed. These actually suppress the over activity of the immune system brought on by the lupus, and help limit the damage and preserve the function of the involved organ. (Lupus is NOT a form of cancer).”

There are many types of chemotherapy agents used in treating lupus. I have looked them up and here are a few of them (from the Lupus Foundation of America website):

Imuran, Cytoxan And Related Drugs

Although immunosuppressive drugs can have serious side effects, they can be of great value in the treatment of systemic lupus erythematosus (SLE). They may help to:

  • prolong life
  • preserve kidney function
  • reduce disease symptoms
  • reduce damage to vital organs, such as the kidneys and lungs.
  • sometimes even serve to put the disease into remission.

Steroids used alone to treat major organ involvement in lupus must sometimes be given in high doses. This increases the risk of short-term and long-term side effects, which may sometimes be worse than the disease itself. Immunosuppressive drugs can be used either in addition to, or instead of, steroids to spare the patient some of the undesirable side effects of steroid therapy.

Thus, immunosuppressive and cytotoxic drugs are used in the treatment of lupus for two major reasons:

  1. They are potent drugs which help to control disease activity in major organs, including the kidney, brain, cardiovascular system, and lungs.
  2. They may reduce or eliminate the need for steroids (cortisone derivatives such as prednisone).

How Do They Work?

Cells in the body divide and grow at varying rates. Examples of rapidly dividing cells include:

Cytotoxic (cyto=cell, toxic=damage) drugs work by targeting these cells which grow at a rapid rate. In lupus, the immune system produces autoantibodies at a rapid rate of growth. Cytotoxic medicines can suppress the cells involved in the hyperactive immune response.

Possible Risks

There are risks associated with the use of cytotoxic drugs.

  • The immune system may be suppressed too much, which causes an increased susceptibility to infection, particularly shingles (a painful, blistering skin condition) and pneumonia.
  • The bone marrow can be suppressed as well, which results in reductions in red blood cells, white blood cells, or clot-forming platelets.
  • Suppression of hair cell growth may lead to overall loss of hair.
  • The cytotoxic effects on gonadal cells can lead to sterility.

Imuran (generic name: azathioprine)

Imuran is less potent and less effective than Cytoxan, but has fewer side effects. Imuran is well tolerated in most cases. Imuran is steroid-sparing and studies have shown that it clearly improves liver and kidney lupus.

Side effects can include:

  • nausea
  • decreases in white blood cell count, platelet count, or red blood cell count
  • increased risk of developing lymphoma (cancer involving the lymph glands, liver and spleen), with long-term Imuran use

Blood tests to determine the white blood cell, platelet, and red blood cell count should be done regularly in patients receiving this drug. Adjustments in dosage are made if the tests indicate a serious decrease in blood counts.

Cytoxan (generic name: cyclophosphamide)

Cytoxan is well tolerated by most patients. Like Imuran, it may cause an upset stomach, and its use may decrease the white blood cell count, platelet count, or red blood cell count

Side effects can include:

  • an increased risk of developing malignancies, including leukemia and bladder cancer, with long-term Cytoxan use
  • temporary or permanent sterility in both women and men, preventing them from having children
  • leading to damage of a developing fetus if a woman gets pregnant while being treated with the drug
  • bleeding from the bladder-this usually can be prevented by drinking large amounts of water
  • causing a predisposition to develop shingles
  • hair loss
  • like Imuran, causing a predisposition to develop unusual infections, particularly when given in combination with high doses of steroids

Blood tests to determine these blood counts should be done regularly for those receiving Cytoxan. If the blood count is seriously decreased, the dosage is adjusted and the blood counts will generally return toward normal.

How Is Cytoxan Administered?

Cytoxan can be given as oral tablets, but more often is given through the vein (intravenously, or IV).

  • This procedure generally takes between 15 and 60 minutes.
  • Large amounts of intravenous fluids are also given to dilute the concentration of Cytoxan in the bladder.
  • Pre-medication for nausea is sometimes given, but treatment with Cytoxan is generally well tolerated.
  • IV Cytoxan seems to be associated with fewer malignancies and many fewer bladder problems, while being equally effective.
  • Controlled studies also show that it improves kidney and autoimmune lung disease.

 

Related Drugs

Leukeran (generic name: chlorambucil) and Mustargen (generic name: nitrogen mustard)

  • These two cytotoxic drugs are related to cyclophosphamide.
  • Both have similar side effects to Cytoxan.

Methotrexate

This drug is usually given orally on a weekly basis, although it may be given by injection.

  • The dosage is generally 7.5 to 25 milligrams per week.
  • Methotrexate is well tolerated by most patients.
  • Its use in lupus has not been thoroughly tested, but it is given commonly for rheumatoid arthritis and has been shown to produce improvement of joint pain and stiffness.
  • It is only modestly effective for organ-threatening lupus.
  • Liver disease and lung reactions can occasionally occur with the use of methotrexate.
  • Blood counts and blood liver enzyme tests should be monitored regularly in patients receiving this drug, and the dosage modified if side effects are detected.

CellCept (generic name: mycophenolate mofetil) and Neoral (generic name: cyclosporine)

  • These two medications modify the immune system, which, in lupus, appears to be both overactive and misdirected.
  • Both of these medications are used to prevent rejection of the donated organ in kidney, liver, heart and lung transplants.
  • CellCept can cause nausea and diarrhea.
  • Cyclosporin may elevate blood pressure and reduce kidney function.

Conclusion

All of these agents are steroid-sparing. While cytotoxic medications should not be used in cases of mild lupus, these medications can be very helpful and even life-saving when major organs are involved, or in cases where the lupus is quite active and symptomatic.

Sometimes a kidney biopsy or other tissue biopsy is necessary before deciding whether to use these drugs. Even in more serious cases of major organ involvement, cytotoxic drugs should not be used indefinitely without good reason.

It is important to weigh the beneficial effects as well as the risks involved in cytotoxic drug therapy. Doctors use the term “risk-benefit ratio” to describe the comparison of side effects to beneficial effects of medication. While these cytotoxic drugs are not FDA-approved for use in SLE, they are commonly used and accepted as standard practice. People with lupus should discuss the risk-benefit ratio of these medications with their physician.

It’s That Time Of The Year

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I bet you thought this would be about the holidays. Well, no, it is about winter.

This is that time of the year where the nights are longer, the air is colder, and we are indoors more. It is also that time of the year when many infectious viruses and bacteria are shared with others as we are indoors and have close contact with each other.

When I was in nursing school, my microbiology professor called this time of year, “a microbiotic soup of those infected and those susceptible”. In short, we are in closed spaces, and around more people and are more prone to the touching of places where some who are sick have touched, walking by someone who is sneezing or coughing and inhaling the germs, or being around a child who may have been exposed to germs at school. Hence the microbiotic soup analogy.

Those of us with lupus have to be more vigilant than most. You see, most of our medications are considered immunosuppressants and can leave us more vulnerable because of our immune systems being lowered. At this point, you may think, “Go get a flu shot”. I must state here that the jury is out in regards to lupus patients and flu shots. Many lupus patients are recommended by their doctors to get flu shots each year. They get them and all is good. Some others are advised by their doctors NOT to get the flu shots. My doctor is one of those who has told me not to get a flu shot.

Some have noticed that lupus patients seem to go into a flare when they get flu shots, others say the opposite. Like I said, the jury is out and since I am no doctor, I say talk to your doctor and follow their advice. It may be that your medications can play a role in whether you should get one or not. The type of lupus may be another reason. In the end, it is best to listen to those who are more qualified and know what the risks versus the benefits are.

Another thing about this time of the year is the colder air and the cold fronts which come through bringing the drop in barometric pressure and to some of us lupies, pain. For some reason, the cold weather makes our joints hurt. I know I experience this. I almost hibernate this time of the year because of it.

Now on a personal note, and in an effort to be honest here, I have found myself not only flaring and in pain, but while out and about (I went to the grocery), I seem to have picked up a nasty cold bug. I am using my neti pot and keeping to comfort foods while resting up and fighting it. Sometimes, when it rains, it pours. Ah well, such is the life of a lupie patient.

The best news of the week is that the FDA committee approved sending Benlysta for final approval for lupie patients. The date it will go in front of the FDA is December 5th. It is imperative that this drug get approved. I am on the clinical trial of this and I inject a dose once every two weeks subcutaneously. The study I am in is different than what is hopefully being approved. The FDA is approving Benlysta for IV infusion for lupus patients. The study I am in is to see the effectiveness of injecting instead of infusing. So, we will hope that it gets approved so many of us can feel better instead of worse this time of the year.

I hope all of you have pain free days and restful nights this winter. Remember to watch out for the bugs which can infect us this time of the year.